Monday, April 18, 2011

Whiplash or Fibromyalgia?

A recent study published in the journal Pain sheds some light on the ongoing debate about the causal relationship between neck injuries sustained during a car accident and the development of the pain condition fibromyalgia. Chiropractors commonly treat patients with both conditions, and separating these diagnoses can improve treatment. The latest research suggests that fibromyalgia may be overdiagnosed in patients who have a history of whiplash injury due to a motor vehicle accident.
People with fibromyalgia experience a range of life-disrupting symptoms, include general and localized pain, fatigue, and difficulty sleeping. Neck and shoulder tenderness is one common indicator that practitioners use to diagnose fibromyalgia; general pain lasting longer than three months is another. However, these symptoms also are common among patients experiencing the lingering effects of whiplash. Some past research has shown that people with neck injuries incurred in a motor vehicle accident are 13 times more likely to develop fibromyalgia than those with other injuries. Other studies have questioned these conclusions.
Researchers at the University of Washington set out to investigate the prevalence of fibromyalgia in whiplash patients with persistent neck pain. They questioned whether the most common set of criteria used for diagnosing fibromyalgia may rely too heavily on evaluating trigger points located in the neck and shoulder. The study participants included 326 individuals with whiplash-associated neck pain that had lasted longer than 3 months. The participants were enrolled in a 6-week treatment program for their symptoms that consisted of educational therapy sessions.
The researchers evaluated the patients for fibromyalgia both at the beginning and the end of the program. Two sets of criteria were used to diagnose fibromyalgia: the standard guidelines and adjusted guidelines that discounted the importance of pain in the neck and shoulder area. Using the standard guidelines, the researchers initially diagnosed 14% of the whiplash participants with fibromyalgia. This rate dropped to 8% using the adjusted guidelines.
These findings suggest that health practitioners who treat patients with persistent neck pain, such as chiropractors, may be led to significantly overdiagnose fibromyalgia in their patients. People with a history of whiplash-associated injuries should be aware of this unintended bias, and report their injury history.

Robinson JP, Theodore BR, Wilson HD, Waldo PG, Turk DC. Determination of fibromyalgia syndrome after whiplash injuries: Methodologic issues. Pain. 2011 Mar 16.

Monday, April 11, 2011

More Reasons to Eat Your Fruits!

Strawberries Fight Cancer, Study Finds

Strawberries have the potential to prevent esophageal cancer, according to a preliminary study released Wednesday.
Researchers, led by Ohio State University, were able to show that freeze-dried strawberries slowed the growth of dysplastic, or precancerous, lesions in about 30 people who consumed the fruit for six months.
The study's lead researcher, Tong Chen, an assistant professor in the oncology division of Ohio State University, presented the study at the American Association for Cancer Research's annual meeting.
0406strawberry
European Pressphoto Agency
Strawberries have the potential to prevent esophageal cancer, according to a preliminary study released Wednesday.
Esophageal cancer is the third most common gastrointestinal cancer and the sixth most frequent cause of cancer death in the world, Dr. Chen said. About 16,000 new cases of esophageal cancer a year are diagnosed in the U.S., according to the American Cancer Society.
Dr. Chen and a group of researchers are studying esophageal squamous cell carcinoma, the dominant type of esophageal cancer world-wide. They are looking at whether food or other substances might prevent cancer. Previous work showed that freeze-dried strawberries were able to significantly inhibit tumor development in rats.
The research team designed a small study in humans and approached the California Strawberry Commission, which agreed to fund the study and make available the freeze-dried strawberries. The commission is a state agency funded by the strawberry industry.
Dr. Chen's team recruited 38 people in China who had mild-to-moderate dysplasia in the esophagus; 36 people completed the study. Biopsies of the esophagus were taken before and after the study. On average, patients were about 55 years old.
They were instructed to consume 30 grams of freeze-dried strawberries dissolved in a glass of water twice daily for a total of 60 grams a day for six months. Dr. Chen said the freeze-dried substance is about 10 times as concentrated as fresh strawberries, but suggested people could still benefit from eating whole strawberries on a daily basis.
Overall, the results showed 29 out of 36 participants experienced a decrease in histological grade of the precancerous lesion, or a slowing in the growth of the lesion during the study. Dr. Chen said larger, randomized placebo-controlled studies are needed to confirm the results. She said it isn't clear exactly what the anti-cancer agent in strawberries might be. But she noted that strawberries contain a variety of vitamins, minerals and other substances known as phytochemicals, which are also found in some other types of berries.
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